Adult
Cefalexin
Warning
General Information
Do NOT use if patient has a history of severe penicillin allergy. If in doubt, discuss with Micro/ID.
Formulary antimicrobial: For details see OUH netFormulary
AWaRe antibiotic classification: 'Access'. Use as per guidelines.
Renal and hepatic impairment
Renal impairment
|
eGFR (mL/min/1.73m2) |
Dose |
|
More than 40 |
Dose as in normal renal function |
|
10-40 |
250-500mg every 8-12 hours |
|
Less than 10 |
500mg every 12-24 hours |
|
HD/HDF/High Flux/PD |
Dose as in eGFR less than 10ml/min/1.73m2 . Dialysed; give after dialysis |
Hepatic impairment
Use with caution in patients with hepatic impairment.
Pregnancy and breastfeeding
Pregnancy
Not known to be harmful in pregnancy
Breastfeeding
Present in milk in low concentrations, but appropriate to use
References
- Summary of Product Characteristics (SPC) for Cefalexin 250mg Capsules Accessed via www.medicines.org.uk 26/03/18. Last updated 07/10/15
- The Renal Drug Database. Cefalexin. Accessed via renaldrugdatabase.com 26/03/18. Last updated 19/12/17