Adult
Doxycycline
Warning
General information
Tablets and capsules are Formulary antimicrobials: Use in accordance with Trust guidelines.
Injection is Restricted formulary antimicrobial: For details see OUH netFormulary
AWaRe antibiotic classification: 'Access'. Use as per guidelines.
Renal and hepatic impairment
Renal impairment
No dose adjustment required in renal impairment. Not dialysed.
Hepatic impairment
Doxycycline should be avoided or used with caution in patients with hepatic impairment. Doxycycline should also be used with caution in those receiving potentially hepatotoxic drugs.
Pregnancy and breastfeeding
Pregnancy
Doxycycline is contra-indicated in pregnancy due to its teratogenic side effects.
Breastfeeding
It should not be given to women who are breastfeeding.
References
- Summary of Product Characteristics (SPC) for Doxycycline 100mg capsules. Accessed via www.medicines.org.uk 26/03/18. Last updated 21/09/17
- The Renal Drug Database. Doxycycline. Accessed via renaldrugdatabase.com 26/03/18. Last updated 20/02/18