Adult

Fidaxomicin

Warning

General Information

Restricted formulary antimicrobial: For details see OUH netFormulary

AWaRe antibiotic classification: 'Watch'. Use as per guidelines. All other indications to be discussed with Micro/ID.

Renal and hepatic impairment

Renal impairment

Dose as in normal function. Unlikely to be dialysed.

 

Hepatic impairment

No dose adjustment is considered necessary. Use with caution in moderate to severe hepatic impairment.

Pregnancy and breastfeeding

No data available for use in pregnancy and breastfeeding, discuss with a pharmacist.

References

  1. Summary of Product Characteristics (SPC) for Dificlir 200mg film-coated tablets. Accessed via www.medicines.org.uk 26/03/18. Last updated 07/09/16
  2. The Renal Drug Database. Fidaxomicin. Accessed via renaldrugdatabase.com 26/03/18. Last updated 20/02/18

Editorial Information

Next review date: 02 Mar 2026