Primaquine

Renal impairment

• Dose adjustment is not required for renal impairment.
• HD: Not dialysed.
• HDF/High Flux/PD: Unknown dialysability.

Hepatic impairment 

No information available for use in hepatic impairment.

Pregnancy

Use only if potential benefits outweigh the risks (risk of neonatal haemolysis and methaemoglobinaemia in third trimester).

Breastfeeding

Discuss with pharmacy

• Use with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency.
• Use with caution in patients with systemic diseases associated with granulocytopenia (e.g. rheumatoid arthritis and lupus erythematosus).

1. Summary of Product Characteristics (SPC) for Primaquine phosphate tablets. Accessed via http://products.sanofi.us/primaquine/primaquine.pdf 07/17.
2. BNF online accessed via www.medicinescompleet.com 9/1/19; last updated 11/12/18