Adult
Rezafungin
Warning
General Information
Echinocandin
Restricted formulary antimicrobial: For details see OUH netFormulary
Standard dose
|
Day 1 of treatment (Loading) |
400mg iv single dose |
|
Day 8 of treatment and onwards (Maintenance) |
200mg iv on day 8 and then once weekly
|
Obesity
No dose adjustment required
Renal and hepatic impairment
Renal impairment
No dose adjustment required
Hepatic impairment
No dose adjustment required
Interactions
See Summary of Product Characteristics and BNF for information about interactions.
Pregnancy and breastfeeding
Pregnancy: Avoid unless benefit to mother outweighs risk to foetus. There is no data from the use of rezafungin in pregnancy. Discuss with Micro/ID and pharmacy.
Breastfeeding: Discuss with pharmacy
Additional information
The OUH Antifungal Patient Information Leaflet can be found HERE
References
- Napp Pharmaceuticals Limited. Summary of Product Characteristics. Rezzayo 200 mg powder for concentrate for solution for infusion [online]. Last revision of the text: 29/1/24. Accessed via: https://www.medicines.org.uk/emc#gref Accessed:17/3/25.
- BNF online accessed via www.medicinescomplete.com. Accessed:11/02/25
- Sanford Guide. Rezafungin [Internet] Last revision of the text: 5/2/25
- Sanford Guide. Obesity dosing adjustment [Internet] Last revision of the text: 23/2/25
- Drugs and Lactation Database (LactMed). Rezafungin [Internet] Last updated May 2023