Adult

Terbinafine

Warning

General Information

Restricted formulary antimicrobial: For details see OUH netFormulary

Renal and hepatic impairment

Dose in renal impairment

eGFR (mL/min/1.73m2) Dose
10-50 Give the full dose on alternate days
Less than 10 Give the full dose on alternate days
HD/HDF/High Flux/PD

Dose as in eGFR less than 10ml/min/1.73m2.

Unlikely dialysability.

 

Use in hepatic impairment

Avoid use in chronic or active liver disease.

Pregnancy and breastfeeding

Discuss with pharmacy.

References

  1. Summary of Product Characteristics (SPC) for Terbinafine 250mg Tablets. Accessed via www.medicines.org.uk 26/03/18. Last updated 31/08/2016
  2. The Renal Drug Database. Terbinafine. Accessed via renaldrugdatabase.com 15/1/19; last updated 1/3/18
  3. BNF online accessed via www.medicinescomplete.com 14/1/19; last updated 23/4/18

Editorial Information

Next review date: 04 May 2026