Adult
Terbinafine
Warning
General Information
Restricted formulary antimicrobial: For details see OUH netFormulary
Renal and hepatic impairment
Dose in renal impairment
eGFR (mL/min/1.73m2) | Dose |
10-50 | Give the full dose on alternate days |
Less than 10 | Give the full dose on alternate days |
HD/HDF/High Flux/PD |
Dose as in eGFR less than 10ml/min/1.73m2. Unlikely dialysability. |
Use in hepatic impairment
Avoid use in chronic or active liver disease.
Pregnancy and breastfeeding
Discuss with pharmacy.
References
- Summary of Product Characteristics (SPC) for Terbinafine 250mg Tablets. Accessed via www.medicines.org.uk 26/03/18. Last updated 31/08/2016
- The Renal Drug Database. Terbinafine. Accessed via renaldrugdatabase.com 15/1/19; last updated 1/3/18
- BNF online accessed via www.medicinescomplete.com 14/1/19; last updated 23/4/18