Adult

Epistaxis - Nasal Packing

When nasal infection or colonisation with Staphylococcus aureus may be contributing to epistaxis, local treatment can be considered.

Outpatient

  • Nasal swabs sent for culture, where possible
  • No antimicrobials are indicated unless infection suspected

Preferred: Naseptin® (chlorhexidine + neomycin) nasal cream

Apply a small amount (about the size of a match head) to both nostrils BD for 5 days

NB: Contra-indicated if patient (or carer) has allergy to chlorhexidine, peanuts or soya 

Alternative: Bactroban® (mupirocin (2% w/w mupirocin free acid)) nasal ointment

Apply a small amount (about the size of a match head) to both nostrils TDS for 5 days

Prolonged/In patient

Preferred: Naseptin® (chlorhexidine + neomycin) nasal cream

Apply a small amount (about the size of a match head) to both nostrils BD for 5 days

NB: Contra-indicated if patient (or carer) has allergy to chlorhexidine, peanuts or soya 

Alternative: Bactroban® (mupirocin (2% w/w mupirocin free acid)) nasal ointment

Apply a small amount (about the size of a match head) to both nostrils TDS for 5 days

There is limited evidence on the use of antibiotics after nasal packing but antibiotics may be considered for an individual patient where nasal infection is suspected:

Preferred: 

Flucloxacillin 500mg po qds for up to 3 days 

Alternative for penicillin allergy (non-severe and severe): 

Doxycycline 100mg po bd for up to 3 days

Consider penicillin allergy assessment and delabelling

Editorial Information

Last reviewed: 01 Nov 2024