Adult

Malaria - uncomplicated

Warning

ALWAYS consult Micro/ID about fever in the returning traveller or a diagnosis of malaria
Severe malaria  - see guideline Malaria - severe

Prescribe using the 'Artesunate/Riamet Initiation for Malaria PowerPlan'

Preferred

Includes all human malaria infections

Riamet® 4 tablets per dose orally taken at 0h, 8h, 24h, 36h, 48h, 60h (with food or milk drink to improve absorption)

  • Riamet® is artemether-lumefantrine (1 tablet = 20mg artemether + 120mg lumefantrine)
  • For patients who are unable to take oral medicines see guideline Malaria - severe
  • AVOID doxycycline at all stages of pregnancy, see guideline Malaria in Pregnancy

Alternative

ONLY indicated if Riamet® is unavailable OR in the case of hypersensitivity/ adverse reaction to Riamet® 

Quinine can be associated with prolonged QT interval. For more information, including MHRA drug safety update, see monograph quinine sulfate   

quinine sulfate 600mg po tds + doxycycline 200mg po od for 7 days 

OR 

quinine sulfate 600mg po tds + clindamycin 600mg po bd for 7 days

Editorial Information

Last reviewed: 01 Aug 2023

Next review date: 01 Aug 2026