Adult
Soft tissue injury, contaminated
For skin and soft tissue wounds that are contaminated but not actively infected.
- Thorough cleaning and/or surgical debridement is indicated.
- Tetanus risk assessment should be performed. See also Tetanus prone wounds.
Suggested duration of antibiotic therapy
- Consider antibiotics for 3 days where heavy contamination has occurred, especially with soil, mud, faeces, and dirty water.
- Consider antibiotics for 5 days where a foreign body has been removed from a contaminated wound.
- When a foreign body cannot be removed, consult Micro/ID
Preferred
flucloxacillin 1g po or iv qds PLUS metronidazole 400mg po tds
Alternative
Penicillin allergy (non-severe and severe) and MRSA positive patients:
co-trimoxazole 960mg po bd
OR
doxycycline 100mg po bd PLUS metronidazole 400mg po tds