Penicillin Allergy: Challenge and Delabelling

Contraindications: 

• Patient clinically unstable
• Pregnant patients
• Uncontrolled asthma
• Unstable Ischemic Heart Disease (IHD)

Discuss delabelling with patient/Power of Attorney (PoA). If patient/PoA consents, document the consent in patient’s EPR record and proceed with delabelling. 

Documenting outcome of penicillin challenge and delabelling

• Modify allergy status on secondary care/primary care notes
  • If allergy disproven, state “Successfully delabelled DD/MM/YYYY: Patient is NOT penicillin-allergic”
  • If allergy confirmed, state “Penicillin allergy CONFIRMED on DD/MM/YYYY– symptoms of XXX”

Inform the patient the outcome of the challenge. If the allergy has been disproved then counsel the patient that they are no longer allergic to penicillins based on your assessment +/- results of challenge.