Vascular Device Placement
Link to General Principles, including redosing table.
For prescribing use Adult Interventional Radiology powerplan on EPR.
If device placement is in the setting of previous or current infection then discuss with Micro/ID for antibiotic regimen tailored to the case.
No antibiotic needed for the following procedures
- Totally Implanted Venous Access Device (TIVAD) insertion or removal
- Peripheral Angioplasty/Stenting
- Deep Venous stenting
- IVC Filter insertion
Insertion or removal of the following
No antibiotics needed for insertion or removal of the following
- Forearm arteriovenous fistula formation (radiocephalic and brachicephalic)
- Tunnelled central intravascular catheter (e.g. Hickman®)
- Non-tunnelled central intravascular catheter
- Totally Implanted Venous Access Device (Portacath®)
- PICC (peripherally inserted central catheter)
- Tunnelled dialysis catheter (e.g. Tesio®)
For selected cases at particularly high risk e.g neutropaenic or haematology/oncology patient, prophylaxis can be considered based on individual patient's circumstance:
Preferred: flucloxacillin 1g iv
For Penicillin allergy (non-severe or severe) or MRSA positive: teicoplanin 800mg iv
Vascular access surgery / insertion
Including:
- All transposition access operations
- Fistula revision or salvage
- Graft insertion (PTFE, omniflo®)
Preferred: including for penicillin allergy (non-severe and severe) or MRSA positive patients: teicoplanin 800mg iv
Vascular procedure with pre-existing indwelling sheath e.g. Follow up thrombolysis
Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below)
cefazolin iv dose | |
Weight under 50kg | 1g |
Weight 50kg to less than 120kg | 2g |
Weight 120kg or more | 3g |
Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis | 1g |
For penicillin allergy (severe) or MRSA positive patients: gentamicin 3mg/kg iv
Aortic Stent Grafting
Preferred (including penicillin allergy (non-severe)): cefazolin iv (see dosing table below) + gentamicin 3mg/kg iv
cefazolin iv dose | |
Weight under 50kg | 1g |
Weight 50kg to less than 120kg | 2g |
Weight 120kg or more | 3g |
Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis | 1g |
For penicillin allergy (severe) or MRSA positive: teicoplanin 800mg iv + gentamicin 3mg/kg iv
Aortic Stent Grafting (HIGH infection risk) and arterial graft interventions
24 hours of antibiotic cover is recommended
NB: the adult interventional radiology powerplan only contains single dose cefazolin and teicoplanin. Prescribers need to prescribe additional cefazolin or teicoplanin doses separately to provide 24 hours antibiotic cover.
Pre-procedure:
Preferred (including penicillin allergy (non-severe)): cefazolin iv (see initial dosing table below) + gentamicin 3mg/kg iv
cefazolin iv dose | |
Weight under 50kg | 1g |
Weight 50kg to less than 120kg | 2g |
Weight 120kg or more | 3g |
Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis | 1g |
For penicillin allergy (severe) or MRSA positive: teicoplanin 800mg iv + gentamicin 3mg/kg iv
Post-procedural antibiotics (to provide 24 hours antibiotic cover):
Preferred (including for penicillin allergy (non-severe)): cefazolin iv for 24 hours, 2g tds but dose will need to be adjusted for renal function
For penicillin allergy (severe) or MRSA positive: teicoplanin 800mg iv single dose at 12 hours post procedure
Transjugular Intrahepatic Portosystemic Stent-Shunt (TIPSS)
Antibiotic prophylaxis is not routinely required unless prolonged/ complex procedure OR biliary puncture occurs OR previous biliary surgery then as below.
Pre-procedure:
Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below)
cefazolin iv dose | |
Weight under 50kg | 1g |
Weight 50kg to less than 120kg | 2g |
Weight 120kg or more | 3g |
Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis | 1g |
For penicillin allergy (severe) or MRSA positive: gentamicin 3mg/kg iv
Post-procedural antibiotics are indicated as per BSG 2019 (reviewed 2024):
Preferred (including for penicillin allergy (non-severe)): cefazolin 2g iv tds for 48h (from first dose preop)
For penicillin allergy (severe) or MRSA positive: gentamicin 3mg/kg iv od for one further dose at 24 hours post procedure
NB: the adult interventional radiology powerplan only contains single dose cefazolin and gentamicin. Prescribers need to prescribe post-procedure antibiotics separately to provide 48 hours antibiotic cover.
Permanent Cardiac Device
See guideline Cardiac and Thoracic Surgery
TAVI
See guideline Cardiac and Thoracic Surgery
Refrences
British Society of Gastroenterology (BSG) 2019 (reviewed 2024) Transjugular Intrahepatic Portosystemic Stent-Shunt (TIPSS) in the management of portal hypertension. (bsg.org.uk)