Adult

Breast Surgery

Warning

 Link to General Principles, including redosing table

Breast surgery without prosthesis

gentamicin 3mg/kg iv OR teicoplanin 800mg iv

Routine post op doses not routinely recommended unless in cases where active infection is present at time of surgery; treat as breast infection.

Breast surgery with prostheses or axillary dissection

Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below)

  cefazolin iv dose 
Weight under 50kg 1g
Weight 50kg to less than 120kg 2g
Weight 120kg or more 3g
Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis 1g

For penicillin allergy (severe) or MRSA positive: gentamicin 3mg/kg iv AND teicoplanin 800mg iv

Routine post op doses not routinely recommended unless in cases where active infection is present at time of surgery, treat as breast infection.

Breast surgery - revision and/or infection

Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below) AND gentamicin 3mg/kg iv

  cefazolin iv dose 
Weight under 50kg 1g
Weight 50kg to less than 120kg 2g
Weight 120kg or more 3g
Creatinine Clearance less than 10ml/min or patient receiving haemodialysis 1g

OR

gentamicin 3mg/kg iv AND teicoplanin 800mg iv

Routine post op doses not routinely recommended unless in cases where active infection is present at time of surgery, treat as breast infection.

Editorial Information

Last reviewed: 27 Oct 2026

Next review date: 04 Oct 2029

Author(s): AMST.