Adult

GIT & Biliary Surgery - Endoscopic procedures

Link to General Principlesincluding redosing table

Endoscopic procedures (gastroenterology)

Antibiotic Prophylaxis is NOT indicated for the majority of patients undergoing endoscopic procedures, including patients with valvular heart disease or prosthetic joints.  

Antibiotic prophylaxis is recommended for

  • patients with severe neutropenia OR haematologic malignancies
  • patients with cirrhosis AND ascites undergoing procedures such as oesophageal dilation or endoscopic sclerotherapy
  • all patients prior to placement of a PEG or PEJ tube.

Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below)

  cefazolin iv dose 
Weight under 50kg 1g
Weight 50kg to less than 120kg 2g
Weight 120kg or more 3g
Creatinine Clearance less than 10ml/min or patient receiving haemodialysis 1g

 

For penicillin allergy (severe) or MRSA positive patients: gentamicin 3mg/kg iv

ERCP (Endoscopic Retrograde Cholangio- Pancreatography): High risk cases

Antibacterials NOT routinely required for ERCP

When complete biliary drainage is unlikely to be achieved AND for sclerosing cholangitisciprofloxacin 750mg po

For cases already being treated for cholangitis: continue treatment antibiotics

Editorial Information

Last reviewed: 01 Feb 2023