Adult

Gynaecological, Urogynaecological and Gynae-oncology Surgery

Warning

Link to General Principles, including redosing table.

  • Routine post op antibiotic doses are not recommended.
  • For cases where active infection is present at the time of surgery - treat as per guidelines.

Gynaecological, Urogynaecological and Gynae-oncology Surgery - clean

Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below)

  cefazolin iv dose 
Weight under 50kg 1g
Weight 50kg to less than 120kg 2g
Weight 120kg or more 3g
Creatinine Clearance less than 10ml/min or patient receiving haemodialysis 1g

For penicillin allergy (severe) or MRSA positive patients: gentamicin 3mg/kg iv

Routine post op doses not routinely recommended unless in cases where active infection is present at time of surgery, treat as per guidance.

Gynaecological, Urogynaecological and Gynae-oncology Surgery - clean contaminated/contaminated

Preferred (including for penicillin allergy (non-severe)): cefazolin iv (see dosing table below) AND metronidazole 500mg iv 

  cefazolin iv dose 
Weight under 50kg 1g
Weight 50kg to less than 120kg 2g
Weight 120kg or more 3g
Creatinine Clearance less than 10ml/min or patient receiving haemodialysis 1g

For penicillin allergy (severe) or MRSA positive patients: gentamicin 3mg/kg iv AND metronidazole 500mg iv

Routine post op doses not routinely recommended unless in cases where active infection is present at time of surgery, treat as per guidance.

Editorial Information

Last reviewed: 27 Oct 2026

Next review date: 22 Oct 2029

Author(s): AMST.