Adult

Transplant Surgery

Link to General Principles, including redosing table

Transplant surgery 1

Includes:

  • Renal transplant
  • Enteric conversion of pancreas transplant

Preferred: meropenem 1g iv (including for penicillin allergy non-severe)

For penicillin allergy (severe) or for MRSA positive patients:

teicoplanin 800mg iv + gentamicin 3mg/kg iv  + If bowel is entered add metronidazole 500mg iv

*Antibiotics are continued post-operatively for intestinal and multi-visceral transplants. See guideline (Speciality Medicine - Transplant)

Transplant surgery 2 (antifungals indicated)

Includes:

  • Pancreas transplant
  • Kidney-pancreas transplant (simultaneous or staggered)
  • Pancreatectomy or exploration of pancreas after transplantation

At induction:

Preferred (including for penicillin allergy non-severe): meropenem 1g iv + Caspofungin 70mg iv. Give second dose of meropenem 500mg iv at 8h post induction

For MRSA positive patients: add teicoplanin 800mg iv single dose

 

For penicillin allergy (severe):

teicoplanin 800mg iv bd +  ciprofloxacin 400mg iv bd  + metronidazole 500mg iv tds for 24 hours + Caspofungin 70mg iv single dose

Islet cell transplant

Preferred (including for penicillin allergy non-severe): meropenem 1g iv

For MRSA positive patients: add teicoplanin 800mg iv 

For penicillin allergy (severe) or for MRSA positive patients:

teicoplanin 800mg iv + gentamicin 3mg/kg iv

Removal of JJ ureteric stent and/or PD catheter (4 weeks post transplant) - under general anaesthetic

Preferred (including penicillin allergy (severe and non-severe)) or MRSA positive patients: gentamicin 3mg/kg iv

Nephrectomy

Includes donor. native, transplanted kidney

Link to Urological surgery

Editorial Information

Last reviewed: 04 Aug 2022