Transplant Surgery
Link to General Principles, including redosing table
Transplant surgery 1
Includes:
- Renal transplant
- Enteric conversion of pancreas transplant
Preferred: meropenem 1g iv (including for penicillin allergy non-severe)
For penicillin allergy (severe) or for MRSA positive patients:
teicoplanin 800mg iv + gentamicin 3mg/kg iv + If bowel is entered add metronidazole 500mg iv
*Antibiotics are continued post-operatively for intestinal and multi-visceral transplants. See guideline (Speciality Medicine - Transplant)
Transplant surgery 2 (antifungals indicated)
Includes:
- Pancreas transplant
- Kidney-pancreas transplant (simultaneous or staggered)
- Pancreatectomy or exploration of pancreas after transplantation
At induction:
Preferred (including for penicillin allergy non-severe): meropenem 1g iv + Caspofungin 70mg iv. Give second dose of meropenem 500mg iv at 8h post induction
For MRSA positive patients: add teicoplanin 800mg iv single dose
For penicillin allergy (severe):
teicoplanin 800mg iv bd + ciprofloxacin 400mg iv bd + metronidazole 500mg iv tds for 24 hours + Caspofungin 70mg iv single dose
Islet cell transplant
Preferred (including for penicillin allergy non-severe): meropenem 1g iv
For MRSA positive patients: add teicoplanin 800mg iv
For penicillin allergy (severe) or for MRSA positive patients:
teicoplanin 800mg iv + gentamicin 3mg/kg iv
Removal of JJ ureteric stent and/or PD catheter (4 weeks post transplant) - under general anaesthetic
Preferred (including penicillin allergy (severe and non-severe)) or MRSA positive patients: gentamicin 3mg/kg iv
Nephrectomy
Includes donor. native, transplanted kidney
Link to Urological surgery