Enteric fever / Typhoid
Consult Paediatric Infectious Diseases
Preferred (including non-severe penicillin allergy)
ceftriaxone 80mg/kg (Max 4g) iv OD (if 1 month old or older)
Switch to oral antibiotics once sensitivities known:
6 months and over: azithromycin 10mg/kg (max 500mg) po OD for total 7 days
Under 6 months: Consult Paediatric Infectious Diseases
Alternative (severe penicillin allergy)
6 months and over: azithromycin 10mg/kg (Max 500mg) po OD for total 7 days
Under 6 months: Consult Paediatric Infectious Diseases
If IV treatment is needed consider: ciprofloxacin* 10mg/kg (Max 400 mg) iv TDS for total 10 days
If patient returning from area where high resistance to ciprofloxacin reported - consult Paediatric infectious diseases
* Note: Ciprofloxacin may induce convulsions in patients with or without a history of convulsions – use with caution.
Also Note: If patient is prescribed ciprofloxacin ensure that the patient is given the Fluoroquinolone MHRA patient information leaflet.
For more information about MHRA safety alerts and patient or carer counselling See Fluoroquinolone antibiotics - paediatric position statement