Intra-abdominal infections (including peritonitis)
Give antibiotics for 48-72 hours and then review.
Preferred
co-amoxiclav 30mg/kg (max 1.2g) iv TDS (BD if 1-2 months old)
If septic add STAT dose gentamicin 7mg/kg iv (max 560mg)
For MRSA positive patients
Add vancomycin iv. Review once microbiology results available.
Alternatives: Penicillin allergy (non-severe)
ceftriaxone 80mg/kg (Max 4g) iv OD
AND metronidazole iv see dosing table below
If septic add STAT dose gentamicin 7mg/kg iv (Max 560mg)
For MRSA positive patients: Add vancomycin iv. Review once microbiology results available.
metronidazole IV dosing:
|
Age |
metronidazole IV dose |
|
1 month up to 2 months |
Loading dose 15 mg/kg (Max 500mg) iv, then (after 8 hours) 7.5 mg/kg (Max 500mg) iv TDS |
|
2 months to 17 years |
7.5mg/kg (Max 500mg) iv TDS |
Alternatives: Penicillin allergy (severe)
ciprofloxacin* 10mg/kg (max 400mg) iv TDS * Ciprofloxacin may induce convulsions in patients with or without a history of convulsions – use with caution
AND metronidazole iv see dosing table below
Consider adding vancomycin iv
For MRSA positive patients: Add vancomycin iv. Review once microbiology results available.
metronidazole IV dosing:
|
Age |
metronidazole IV dose |
|
1 month up to 2 months |
Loading dose 15 mg/kg (Max 500mg) iv, then (after 8 hours) 7.5 mg/kg (Max 500mg) iv TDS |
|
2 months to 17 years |
7.5mg/kg (Max 500mg) iv TDS |