Paediatric

Pinna cellulitis / perichondritis

Warning

Including complications of piercings or otitis externa. 

Treat for 5 days. Can be extended to 7 days, depending on severity and response to treatment.

Pinna cellulitis WITHOUT piercing involvement, and NO evidence of perichondritis and NO evidence of pseudomonas aeruginosa

Preferred

flucloxacillin po (see dosing table)

Age

flucloxacillin oral dose

1 month - 1 year

62.5mg–125 mg QDS

2 years - 9 years

125mg–250 mg QDS

10 years - 17 years

250mg–500 mg QDS

For severe infection: flucloxacillin 50 mg/kg (Max 2g) iv QDS

 

Alternative

Non-severe penicillin allergy or unable to swallow tablets: cefalexin 25 mg/kg (Max 1g) po TDS

Severe penicillin allergy or MRSA positive patients: co-trimoxazole po (see dosing table)

Age

co-trimoxazole oral dose

6 weeks to 5 months

120 mg BD

6 months to 5 years

240 mg BD

6 years to 11 years

480 mg BD

12 years to 17 years

960mg BD

 

Pinna cellulitis WITH piercing involvement OR evidence of perichondritis OR pseudomonas aeruginosa on culture

Preferred, including penicillin allergy non-severe: ceftazidime  50 mg/kg (Max 2 g) iv TDS

Review IV daily and switch to oral when possible: ciprofloxacin* 20mg/kg (Max 750mg) po BD 

 

For penicillin allergy (severe)

ciprofloxacin* 20mg/kg (Max 750mg) po BD

 OR

ciprofloxacin* 10mg/kg (Max 400mg) iv TDS  

 

Note: Ciprofloxacin may induce convulsions in patients with or without a history of convulsions – use with caution

Also Note:  If patient is prescribed ciprofloxacin ensure that the patient is given the Fluoroquinolone MHRA patient information leaflet

For more information about MHRA safety alerts and patient or carer counselling See Fluoroquinolone antibiotics -  paediatric position statement

Editorial Information

Last reviewed: 22 Apr 2026

Next review date: 20 Apr 2029

Author(s): AMST.