Cellulitis (severe)

Consult Paediatric ID

Initial IV therapy with oral stepdown recommended. Review at 24-48 hours.

Open all

flucloxacillin 50mg/kg (Max 2g) iv QDS

cefazolin 50mg/kg (Max 2g) iv TDS

For penicillin allergy (non-severe)

cefazolin 50mg/kg (Max 2g) iv TDS

For penicillin allergy (severe)

clindamycin 10mg/kg (Max 600mg) iv QDS

For MRSA positive patients: ADD vancomycin iv

Review once microbiology results available

Last reviewed: 24 Sept 2025

Next review date: 01 Sept 2028

Author(s): AMST.

Approved By: MMTC

Preferred