Paediatric

Infected eczema (Herpeticum)

  • Treat for 5 days.
  • Also prescribe emollient and topical steroids of appropriate potency (see OUH dermatology guideline). Eczema is often undertreated due to use of inappropriately low potency corticosteroids. Topical steroids are required to reduce inflammation especially if secondary infection is suspected.
  • Patients require isolation until MRSA swab results available. Use standard infection control measures
  • Consider also prescribing antibiotics as secondary bacterial infection is common Infected eczema (Bacterial, mild-moderate) and Infected eczema (Bacterial, severe) 
  • Take bacterial and viral swabs (for HSV, VZV) prior to starting treatment.
  • Consult Paediatric ID and Dermatology if necessary. If eczema herpeticum involves the skin around the eyes, the child should be referred for same-day ophthalmological and dermatological advice.

Preferred

1 month - 11 years:  aciclovir po (see oral dosing table) or iv (see iv dosing table).  For immunocompromised patients refer to BNFc for aciclovir dosing


12 years and over:  valaciclovir po 500mg BD or aciclovir iv (see iv dosing table).  For immunocompromised patients refer to BNFc for aciclovir dosing

 

Aciclovir ORAL dosing table

(NOTE: For immunocompromised patients refer to BNFc for aciclovir dosing)

Age aciclovir  ORAL dose
1-23 months 100 mg 5 times a day
2-11 years 200 mg 5 times a day

NOTE: For patients 12 years and over, valaciclovir is the first line oral agent, see above for dosing.

 

Aciclovir IV dosing table

(NOTE: For immunocompromised patients refer to BNFc for aciclovir dosing)

Age

aciclovir IV dose

Under 3 months

20mg/kg TDS and discuss with paediatric ID

3 months - 11 years

250mg/m2 TDS

12-17 years

5mg/kg TDS

Editorial Information

Last reviewed: 01 Aug 2021

Author(s): AMST.

Approved By: MMTC