Paediatric

Surgical Site Infection

Review after 48 hours.

Consider anaerobic cover if relevant.

Always consider the need for imaging and surgical debridement.   

Take swabs for culture before starting antibacterial treatment.  

Preferred

co-amoxiclav po (see dosing table below)

Age

co-amoxiclav oral dose

1 month to 11 months

0.5mL/kg of 125mg/31mg/5mL suspension TDS

1 year to 5 years

10mLs of 125mg/31mg/5mL suspension TDS

6 years to 11 years

10mLs of 250mg/62mg/5mL suspension TDS

12 years to 17 years

One 625mg tablet TDS OR 10mLs of 250mg/62mg/5mL suspension TDS if patient cannot take tablets 

 

If severe infection consider:  

co-amoxiclav 30mg/kg iv BD if 1-2 months old

co-amoxiclav 30mg/kg (Max 1.2g) iv TDS if 3 months - 17 years

 

Alternative

For penicillin allergy (non-severe and severe)

clindamycin 6mg/kg (max 450mg) po QDS OR clindamycin 10mg/kg (max 600mg) iv QDS if severe infection or unable to tolerate orals

 

If surgery involving GI tract, perineum or uro-genital tract: add ciprofloxacin* 20mg/kg (max 750mg) po BD. If unable to tolerate orals ciprofloxacin* 10mg/kg (max 400mg) iv TDS

*Ciprofloxacin may induce convulsions in patients with or without a history of convulsions – use with caution

Editorial Information

Last reviewed: 01 Jul 2020

Author(s): AMST.

Approved By: MMTC