Paediatric
Pertussis prophylaxis
Preferred
azithromycin 10mg/kg (Max 500mg) po OD for 3 days.
Alternative
Where macrolides are contra-indicated or not tolerated: co-trimoxazole po (see dosing table)
| Age | co-trimoxazole oral dose |
| 6 Weeks to 5 Months | 120mg BD for 7 days* (off label) |
| 6 Months to 5 Years | 240mg BD for 7 days* (off label) |
| 6 Years to 11 years | 480mg BD for 7 days* (off label) |
| 12 years to 17 years | 960mg BD for 7 days* (off label) |
References
UK Health Security Agency. Guidance on the management of cases of pertussis in England during the re-emergence of pertussis in 2024. Updated: June 2024. Available at: Pertussis: guidelines for public health management - GOV.UK (www.gov.uk)