Paediatric
Craniofacial surgery (fronto-facial advancement)
Link to General Principles of Surgical Prophylaxis including redosing table and renal dosing for cefazolin.
Continue antibiotics for 5 days post-op.
Preferred
cefazolin iv see dosing table below
| Weight | cefazolin iv dose |
| Weight less than 120kg | 30mg/kg (maximum 2g) |
| Weight 120kg or more | 3g |
For post-op doses: co-amoxiclav 30mg/kg (max 1.2g) iv TDS (BD for patients 1-2 months old) for 5 days post-op
Alternative
Penicillin allergy (non-severe)
cefazolin iv see dosing table below
| Weight | cefazolin iv dose |
| Weight less than 120kg | 30mg/kg (maximum 2g) |
| Weight 120kg or more | 3g |
For post-op doses: ceftriaxone 50mg/kg (max 2g) iv OD for 5 days post-op
Penicillin allergy (severe) or MRSA positive
teicoplanin 10 mg/kg (Max 800 mg) iv BD for 3 doses then 10 mg/kg (Max 800 mg) iv OD. Duration of 5 days post-op.
AND
metronidazole 30mg/kg iv (Max 500mg) in theatre then continue metronidazole at 7.5mg/kg (Max 500mg) iv TDS. Duration of 5 days post-op.