Paediatric

Open fracture, at primary wound excision + stabilisation

Link to General Principles of Surgical Prophylaxis including redosing table and renal dosing for cefazolin.

Preferred (including non-severe penicillin allergy)

gentamicin 2.5mg/kg iv (max 480mg) 

AND

cefazolin iv see dosing table below

Weight cefazolin iv dose
Weight less than 120kg 30mg/kg (maximum 2g)
Weight 120kg or more 3g

Alternative

For penicillin allergy (severe) or MRSA positive

teicoplanin 10mg/kg iv (Max 800mg)

AND

gentamicin 2.5mg/kg iv (Max 480mg)

Editorial Information

Last reviewed: 01 Nov 2023

Author(s): AMST.

Approved By: MMTC