Augmentation cystoplasty (involving small bowel)
Link to General Principles of Surgical Prophylaxis including redosing table and renal dosing for cefazolin.
Continue oral antibiotics for 5 days post-operatively.
Preferred
metronidazole 30mg/kg iv (Max 500mg)
AND
cefazolin iv see dosing table below
| Weight | cefazolin iv dose |
| Weight less than 120kg | 30mg/kg (maximum 2g) |
| Weight 120kg or more | 3g |
Post op doses: co-amoxiclav po (see dosing table) for 5 days post-op
|
Age |
co-amoxiclav oral dose |
|
1 to 11 months |
0.25mL/kg of 125/31mg/5mL TDS |
|
1-5 years |
5mL of 125/31mg/5mL TDS |
|
6-11 years |
5mL of 250/62mg/5mL TDS |
|
12-17 years |
250/62mg TDS (½ x 625mg tablet TDS OR 5mL of 250/62mg/5mL TDS) |
Alternative
For penicillin allergy (non-severe)
metronidazole 30mg/kg iv (Max 500mg)
AND
cefazolin iv see dosing table below
| Weight | Cefazolin iv dose |
| Weight less than 120kg | 30mg/kg (maximum 2g) |
| Weight 120kg or more | 3g |
Post op doses: trimethoprim 4mg/kg (Max 200mg) po BD for 5 days post-op
For penicillin allergy (severe) or MRSA positive
teicoplanin 10mg/kg iv (Max 800mg)
AND gentamicin 2.5mg/kg iv (Max 480mg)
AND metronidazole 30mg/kg iv (Max 500mg)
Post op doses: trimethoprim 4mg/kg (Max 200mg) po BD for 5 days post-op