AHAH: Respiratory Infection
Community Acquired Pneumonia, including COPD exacerbation
Mild severity
Duration: 3-5 days
Antibiotic Regimens:
|
Route |
Antibiotic and Dosage |
Notes |
|
Oral (Preferred) |
doxycycline100mg po BD |
Can also be 200mg po OD |
|
amoxicillin 500mg po TDS |
|
|
|
clarithromycin 500mg po BD |
Only use if unable to use doxycycline or amoxicillin |
|
|
IV (Aim for rapid oral switch) |
azithromycin 500mg iv OD |
|
|
amoxicillin 1g iv BD |
|
Moderate severity, or where hospital avoidance is preferred
Duration: 5 days
Antibiotic Regimens:
|
Route |
Antibiotic and Dosage |
Notes |
|
Oral (Preferred) |
amoxicillin 500mg po TDS AND doxycycline 100mg po BD |
Doxycycline can also be 200mg po OD |
|
clarithromycin 500mg po BD |
|
|
|
doxycycline 100mg po BD |
If amoxicillin unsuitable, use doxycycline monotherapy Doxycycline can also be 200mg po OD |
|
|
IV (Aim for rapid oral switch) |
amoxicillin 1g iv BD AND azithromycin 500mg iv OD |
|
|
amoxicillin 1g iv BD AND clarithromycin 500mg iv BD |
|
|
| azithromycin 500mg iv OD | Option if amoxicillin unsuitable | |
| clarithromycin 500mg iv BD | Option if amoxicillin unsuitable |
Healthcare Associated Pneumonia (including Aspiration Pneumonia)
Duration: 3 or 5 days
Antibiotic Regimens:
|
Route |
Antibiotic and Dosage |
Notes |
|
Oral (Preferred) |
amoxicillin 500mg po TDS |
|
|
co-trimoxazole 960mg po BD |
Pause ACE inhibitors/Angiotensin receptor blockers or Potassium sparing diuretics |
|
|
IV (Aim for rapid oral switch) |
amoxicillin 1g iv BD |
|
|
co-trimoxazole 960mg iv BD |
Pause ACE inhibitors/Angiotensin receptor blockers or Potassium sparing diuretics |