Adult

COPD: infective exacerbation

  • Antimicrobials are only indicated if patient is febrile or has purulent sputum.
  • See NICE NG115 (revised 2019)

Treatment duration: 3-5 days

Review empirical treatment within 48 hours

Preferred

amoxicillin 500mg po tds 

Alternative

For penicillin allergy, mild or severe

doxycycline 100mg po bd (Discuss with Micro/ID if patient is pregnant)

Consider penicillin allergy assessment and delabelling

Editorial Information

Last reviewed: 31 Jan 2025