Adult
Obstetric Surgery
See General Principles, including redosing table
See also Intra-partum prophylaxis for group B streptococcus (GBS)
Perinatal surgery
For the following procedures:
- Instrumental delivery, including vacuum extraction and forceps
- Caesarean delivery
- Postnatal surgery
- Cervical cerclage
Preferred:
Including for penicillin allergy (non-severe): cefazolin iv (see dosing table below)
| cefazolin iv dose | |
| Weight under 50kg | 1g |
| Weight 50kg to less than 120kg | 2g |
| Weight 120kg or more | 3g |
| Creatinine Clearance less than 10ml/min or patient receiving Haemodialysis | 1g |
For penicillin allergy (severe) and for MRSA positive patients:
teicoplanin 800mg iv + gentamicin 3mg/kg iv
Termination of Pregnancy
doxycycline 100mg bd po for 3 days
Threatened pre-term labour
No antibiotics required
Pre-term pre-labour rupture (PPROM)
Preferred: erythromycin 250 mg qds po for 10 days or until the woman is in established labour (whichever is sooner)
Alternative: amoxicillin 500mg tds po for 10 days or until the woman is in established labour (whichever is sooner)
Missed abortion
No antibiotics required